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Updated on 25/11/2005
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THIS WEEK 

25 November 2005

SNECMA's PPS-1350 ion engine will provide SMART-1's primary propulsion. Illustration by AOES Medialab, ESA. 

Plenty to think about

It's been a fascinating week. First the Japanese appear to be bucking the trend to confuse food with medicine, then we discover that drug side effects are killing the aged, next that there's a new tool to produce realistic-looking prototypes.

Then, just as Gordon Brown tried to pre-empt debate on Adair Turner's report into the UK pension crisis, we found out how much we will need for a comfortable old age (more than you think, surprise, surprise.) But we might be able to do it if we stop trying to reinvent ourselves, says a Kent researcher.

On a completely trivial note, but one with massive potential for those involved, we discovered that soon we may be able to swop Colgate for Wrigley's as the mainstay supplier of our mouth hygiene programme. 

Slim times ahead

Just as the idea of eating your way to health and beauty takes off in the West, Japanese market researcher Fuji Keizai reports that its home market for health and beauty-oriented food products will drop about 7% from 2004 to 1.2 trillion yen ($9.8bn) in 2005 and further to 1.15 trillion yen ($9.6bn) in 2006.

The big sector drops are in life-style related disease prevention and multi-balance food products. But it expects growth in diet, nutritional balance and cavity prevention.

Specifically, the diet sector will reach 63.5bn yen ($530m) in 2006, up 53.8% from 2004; the nutritional sector will expand to 70.5bn yen ($590m) in 2006, up 7.2% from 2004; and the cavity prevention sector will rise to 79bn yen ($660m) in 2006, up 4.8% from 2004. (See Watch out Colgate! Here comes Wrigley's.) 

DNA testers start to prey

Two stories this week suggest that private DNA tests are going to be big, and never mind the ethics.

Under the headline Drug Side Effects Kill Tens of Thousands of Seniors Annually, US-based Genelex Corporation announced a 10% discount on DNA-based drug reaction tests for 55s and older.

It quoted research published in JAMA saying adverse drug reactions are thought to cause more than 100,000 deaths and two million "serious events" every year. It went on to say that oldies are more at risk because 90% of plus-65 year-olds have at least one prescription, 40% five or more and 12% 10 or more.

It put up "a new, free Internet site" www.genemedrx.com where folks can see if DNA tests could them help evaluate their responses to the medicines they are taking. The software program also checks for interactions between certain foods, over-the-counter medicines, and natural remedies with prescription drugs.

Tests for each of four drug metabolism pathways cost $250, or $800 for all four, with a 10% discount for seniors and the military.

---

The other DNA story concerns a Newcastle University skin cancer expert. Together with a chain of cosmetic surgery clinics the professor has set up to test for sun damage to the skin cells' DNA.

For GBP250 you receive a consultation where you fill in a lifestyle questionnaire and take the test. Three weeks later at a second consultation they give you the results and personalised advice on how to look after your skin.

The professor is currently "developing the next generation of sun creams", and no doubt you will also be advised how surgery can undo the ageing effects of the sun.

Curiously, the test won't reveal if you have skin cancer, currently the fastest-growing cancer type in the UK.

WYSIWYG

What you see is what you get. That's the idea behind a database that records the qualities of materials and how they look and behave. Combining this data with a 3D computer-aided design produces a photo-real image of the planned product.

Illustration: ESA

The system had its road test picturing an ion drive engine that will go into the European Space Agency's SMART-1 mission to the Moon.

News'Uproduction, a French start-up company which developed the program, has attracted more money from ESA's European Space Incubator to push its development.

Chief executive Jean-Luc Atteleyn aims to produce photo-quality images and animations of industrial items while they are still in design.

They use standards defined by the International Commission on Illumination (CIE) to describe visual appearance. The database stores the optical behaviour and visual appearance of materials together with other characteristics and physical properties.

Users can then see the optical behaviour of a material in normal pre-defined conditions, and it lets them modify the visual appearance of an object by changing the composition of the material.

New materials could be specified using criteria such as lighting, colour and iridescence, or mechanical properties such as water and thermal resistance, hardness and durability. This "material composer" could meet industrial needs to combine several end-product requirements with final appearance, says the company.

Marc van Eesbeek, head of ESA's materials physics and chemistry section, reckons that in future developers could define the thermal-optical properties of materials in the UV and infrared frequency band, or simulate the temperature and lifetime consequences on structures, and maybe find new potential solutions via their materials database.

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Still on databases is news of The History of European Food Composition Databases, which outlines the many uses and users of food composition tables, and some of the key events in the development of these handy databases. 

Copies of the 62-page paperback, which is published by the British Nutrition Foundation in association with the EuroFIR project, are available free from c.musgrove@nutrition.org.uk.

Bunny-huggers rejoice!

Here at innOvations we applaud all efforts to reduce unnecessary pain and suffering anywhere, any time. So we were happy to hear that scientists at the Technische Universitaet Dresden in Germany are helping to develop BioSim, a computer model that will allow drug researchers to test the effects of new drugs without using as many living creatures as before.

The five-year 10.7m euro EU project hopes to develop a model of drug metabolism as well as approaches to the biosimulation of diabetes, cardiac arrhythmia, neurologic/psychiatric disorders and tumour diseases.

The TU Dresden working group recently demonstrated its novel approach in predicting drug metabolism using the model drug compound chloramphenicol, an antibiotic used to treat aerobic bacteria, mycoplasma, Chlamydial organisms, and anaerobic bacteria.

How much is enough?

It's a tough question, to which the answer usually is, it depends.

But brave souls at the London School of Hygiene & Tropical Medicine have worked out the minimum personal income needed for healthy retirement for the first time. The scary thing is, a lot of us won't make it.

The researchers found that a single person over 65, living independently in the community in England and without a significant disability, needs a minimum of GBP122.70 a week to live healthily, while a couple requires GBP192.60.

The current full basic state pension in the UK is GBP82.05, but this varies with an individual's circumstances.

The researchers' figures include food, the costs associated with exercise (such as entry to swimming baths), housing maintenance and repair costs, dental and eye care costs, and membership costs of social clubs and the like, but not rent or council tax payments, which have been accelerating at double the rate of the consumer price index.

They reckon that to stay healthy, over 65s need to spend GBP32.30 on average on good food, but that those in the lowest 40% of income are spending only GBP23.40.

Although older people can exercise for as little as GBP2.10 a week, over 90% of over 75s are not meeting international guidelines of half an hour of moderate intensity exercise at least five days a week.

The UK has nearly 8m aged 65 and over. The proportion over 85 rose from 0.7% in 1961 to 1.9% in 2002 and is projected to rise to 3.8% in 2031.

The report's chairman, Professor Jerry Morris says "While we are being urged to make healthy choices in the way we lead our lives, older people on government minimum fixed incomes are, on the team's analysis, not able to meet these minimum costs for a healthy life."

Chancellor Gordon Brown has already warned that whatever changes to the state pension strategy that Adair Turner recommends next week should be "affordable". Let's hope government-induced pet food for OAPs is not on the menu.

We're shopping for the emperor's new clothes

Of course, we might not need a state pension if we respond appropriately to University of Kent's Professor Anthony Elliott, who says shopping is ruining us.

Elliott contends we are addicted to reinventing ourselves and instant gratification. As a result we are going broke fast.

Consumers are so bewitched by seductive services, designer goods and hi-tech products that they become addicted to spending, he says. This addiction is blind to the economic and emotional costs of debt and the dangers of insolvency.

"Those addicted to shopping are increasingly reliant on easily available credit. But the explosion in the number of Britons now with serious debt indicates that the problem runs much deeper than easy credit.

"This goes to the core of our quick-fix culture, and it is something that the government needs to consider seriously if it wants to influence the way people live now."

The Department of Trade and Industry showed this month that Britons owe more than GBP1 trillion. Britons' personal debt is now rising at GBP1 million every four minutes. The interest on that debt is around GBP6 billion a month, and 246 plastic-based transactions take place every second in the UK. Personal bankruptcies have soared almost 50% to record levels.

Some economists argue that credit-funded consumer spending has shielded Britain from recession. But Elliott says globalisation creates new personal vulnerabilities. "Employment is more fluid and everything moves incredibly fast. (Apart from the threat to jobs that create wealth as opposed to those that simply move it around), there is increased pressure on people to be seen to try to 'improve' and 'transform' themselves. Consumerism offers just such a road to instant change."

Elliott argues that the emotional costs of quick-fix consumerism are ruining lives. "In some cases, the reinvention craze centred on compulsive consumerism is actually eroding people's inner lives. Shopping as means of transforming oneself is producing a kind of self-mutilation of the psyche."

You can read more on this in Elliott's new book The New Individualism: The Emotional Costs of Globalization published by Routledge. 

Tetra Pak seeks help

Tetra Pak has signed a joint venture agreement with US-based sterilisation and decontamination experts Steris.

The news come hot on the heels of reports that its ink was responsible for contaminating the infant milk packaging at the centre of the latest Nestle scandal.

The JV aims "to support the creation of customised sterilisation systems that address the needs of the food and beverage industry."

Steris will provide technical sterilisation technologies and related capabilities. Tetra Pak will provide expertise in food and beverage production and packaging and related products.

Watch out Colgate! Here comes Wrigley.

Materials, one of Nature's progeny, reports that protein-powered chewing gum may replace the toothbrush for those on the move. Primary target is the military, but the real market is anyone who hates brushing their teeth, or who can't do it conveniently.

The gum, developed by US Army researchers, contains a protein that attacks the bacteria that cause plaque. Plaque can lead to gum infections and tooth decay. The developers believe the gum will keep mouths bacteria-free without the nasty side-effects found in competitive products.

Apparently, untended mouth problems have severe effects on soldiers' morale and hence fighting capacity. Small wonder then in the Army's interest in the gum's active ingredient, a protein fragment called KSL.

In the lab KSL kills harmful mouth bacteria such as Streptococcus mutans by targeting and attacking their cell membranes. The next step is field trials.

Here's hoping they also make the gum biodegrabable after use.

Until next time. 

-- 

Ian Grant 

 
Friday, 25 November 2005
Events
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The British Nutrition Foundation is holding a conference on Agro-food technologies: Opportunities and barriers to improving health.

Date: Friday 9th December 2005

Purpose: to highlight the potential of existing and new technologies in improving the nutritional composition of animal and plant foods to benefit health, particularly in relation to the metabolic syndrome. 

The workshop will also discuss the economic implications of modifying the nutritional composition of these foods, in relation to the findings of the economics workpackage of the EU-funded Lipgene project.

It is aimed at small-to-medium sized enterprises, policy makers, opinion formers and the media.

For a registration form please click here.